MyBioSource.com's Anti-P-Glycoprotein(MDR) antibody (monoclonal) is a Mouse monoclonal antibody. The Anti-P-Glycoprotein(MDR) antibody (monoclonal) was generated using ABCB1, Abcb1a, Abcb1b, ATP-binding cassette, sub-family B (MDR/TAP), member 1A, CD243, and MDR as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Description: Mouse IgG monoclonal antibody for P-Glycoprotein (MDR), ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human. No cross reactivity with other proteins. Uniprot ID: P08183
Background: P-Glycoprotein, also known as Multidrug Resistance 1(MDR1), is one of the ATP-binding cassette transporters family. P-glycoprotein-1 is involved in the transport of 3 of these protease inhibitors in vitro. MDR1 gene is mapped to the 7q21.1 by in situ hybridization. The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin